Journal des troubles génétiques et rapports génétiques

Genetic Disorders and Therapeutic Interventions: Precision Medicine

Damon Salvatore

Genetic disorders, resulting from alterations in an individual's genetic material, pose significant challenges to affected individuals and their families [1]. However, with advancements in genetics and molecular biology, therapeutic interventions for genetic disorders have witnessed remarkable progress. Precision medicine, a tailored approach based on an individual's unique genetic makeup, holds immense promise in the diagnosis, treatment, and management of genetic disorders [2]. Genetic disorders arise from abnormalities in an individual's DNA, which can include gene mutations, chromosomal rearrangements, or variations in the number of chromosomes. These genetic alterations can affect protein function, cellular processes, and overall development, leading to a wide range of disorders [3]. Genetic disorders encompass a broad spectrum of conditions, including monogenic disorders caused by mutations in a single gene, chromosomal disorders resulting from changes in chromosome structure or number, and multifactorial disorders influenced by a combination of genetic and environmental factors.