Journal de médecine régénérative

Intradiscal Injection of Dehydrated Human AmnionChorion Membrane for Treatment of Chronic Discogenic Low Back Pain: A Case Series

Sean A. Lacey, Steven P. Cohen and Michael B. Jacobs

Discogenic Low Back Pain (DLBP) is a common condition with an unfavourable prognosis and limited treatment options. After  experiencing insufficient response to standard conservative care of physical therapy, non-steroidal anti-inflammatory medications andactivity modification, three patients with chronic DLBP were treated with intradiscal injection of dehydrated Human Amnion Chorion Membrane (dHACM). Diagnosis was established by Magnetic Resonance Imaging (MRI) revealing disc disease with anatomically concordant pain.results indicated a trend toward reduced pain as measured by the Numerical Rating Scale for pain (NRS-Pain) and increased function as measured by the Oswestry Disability Index (ODI).