Journal des techniques immunologiques et des maladies infectieuses

A Study on Japanese Encephalitis in and around Kanpur, Uttar Pradesh, India

Jaya Garg, Navneet Kumar, Atul Garg, Upadhyay GC, Yashwant K Rao and Tripathi VN

A Study on Japanese Encephalitis in and around Kanpur, Uttar Pradesh, India

Japanese encephalitis (JE), is mosquito borne viral disease, caused by arbovirus; a member of the family Flaviviridae and is transmitted to humans through a pig-culex mosquito-pig cycle. Humans are an incidental host and most infections of JE virus are asymptomatic. The ratio of unapparent to apparent infection is 200:1 to 300:1 but if clinical illness develops, it causes significant morbidity and mortality. Approximately 3 billion people and 60 per cent of the world population live in JE-endemic regions, and inspite of being a vaccine preventable disease there are approximately 50,000 cases and 15,000 deaths per annum notified from wide geographical range, and half of the survivors suffer severe neuropsychiatric sequelae of the disease.