Journal de biochimie et de physiologie

RNA Interference (RNAi): Eukaryotic Regulatory System

Petro Scott

A powerful technique for the investigation and control of gene expression is RNA Interference (RNAi), also known as PostTranscriptional Gene Silencing (PTGS). A biological process known as RNA Interference (RNAi) involves the involvement of RNA molecules in the sequence-specific inhibition of gene expression by double-stranded RNA via transcriptional or translational repression. The potential for RNAi to inhibit desired genes is enormous. In eukaryotes, gene silencing by RNAi is a normal genetic mechanism that happens after transcription.