Arif Khan*, Vamshi Krishna
Treatment of advanced gastric cancer not amenable for surgery has undergone constant refinements in recent past. The plethora of choices available makes the choice of first line treatment highly complicated. Despite recent advances in systemic therapy survival has marginally improved. FLOT has improved survival markedly in locally advanced gastric cancer amenable for surgery. FLOT is quite active in advanced gastric cancer and reasonably safe. This regimen needs to be further explored in advanced gastric cancer.
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