Andrologie et gynécologie : recherches actuelles

Bacterial Uropathogens in Urinary Tract Infections and antibiotic Susceptibility patterns in Banadir Hospital, Mogadishu-Somalia

Mohamed Hayir Tahlil Mohamud*, Yusuf Omar Mohamed, Abdullahi Adan Shaba, Samira Nur Elmi, Abdulahi Suleiman Hassan, Maryam Ahmed Mohamoud and Mohamed Omar Abdikadir

Background: Urinary tract infection (UTI) is one of the commonest infections encountered by clinicians and despite the widespread availability of antimicrobial agents. UTI has become difficult to treat because of appearance of pathogens with increasing resistance to antimicrobial agents. This study aimed to demonstrate the bacterial Uropathogens causing UTI and their antimicrobial susceptibility patterns. Methods: A descriptive cross-sectional study was used. A non-probability convenient sampling was used for recruitment participants. Clinically suspected patients complaining about UTI were instructed to collect mid-stream urine in a sterile leak proof container. Dipstick, microscopy and culture and sensitivity were performed for each of the urine samples. CLED medium was used for the isolation of bacterial Uropathogens. Susceptibility test was conducted for the bacteria isolated using Kirby-Bauer disk diffusion method. Results: The prevalence of UTI was found to be 81.9% with 70.8% from Female and 11.1% from Male. The isolated Uropathogens were Escherichia coli (56.4%), Klebsiella pneumoniae (30.7%), Enterococcus fecalis (3.6%), Enterobacter (3.6%), Pseudomonas aureginosa (2.8%), Staphylococcus saprophyticus (2.8%). The major antibiotics found to be resistant to isolates were; Ampicillin (93.6%), Augmentin (87.2%), Cotrimazole (85.7%). All isolates of E.coli and Klebsiella pneumonia showed the highest percentage of resistance to Ampicillin and Augmentin while the least resistance was observed against drugs such as nitrofurantoin and Ciprofloxacin. Conclusion: In this study, the prevalence of UTI was 81.9%. Escherichia coli and K. pneumoniae are the major Uropathogens causing UTI among studied patients. Ampicillin showed the highest resistance against the isolated Uropathogens. Nitrofurantoin was the most sensitive followed by ciprofloxacin and ceftriaxone as compared with other antibiotics used in this study.