Journal international de pathologie ophtalmique

Unilateral Posterior Scleritis and Exudative Retinal Detachment Complicating a Single Zoledronate Infusion for Osteoporosis

Shuang Song, Zi-an Shi, Hong Dai and Xiao-bing Yu

We reported the severe adverse event of zoledronate infusion. The point of our case is to emphasize the importance of early recognition of potentially sight-threatening ocular conditions especially the glaucoma or ocular inflammations, as they are readily treatable. Patients also should be informed of these ocular complications, especially at initiation of bisphosphonate therapy and be advised to report any eye symptoms to their physicians. Moreover, doctors should also use bisphosphonates with caution in patients who have a history of glaucoma.