Journal de néphrologie et des maladies rénales

Clinical effectiveness to use of peritoneal dialysis in children with ARF after surgical correction of congenital heart defects

Mekenbaeva R.T

The purpose of research - determine the clinical efficacy of peritoneal dialysis (PD) in children with acute renal failure after correction of complex congenital heart disease (CHD). Methods - examined 52 patients aged 1 month. up to 4 years on the background with ARF after cardiac surgical correction of CHD, who were selected in 2 groups: group 1 - 30 children without PD, 2nd group - 28 children with PD. Children with oligoanuria in both groups conducted diagnostic tests of blood levels of urea and creatinine determination of creatinine clearance and urea clearance, echocardiography-control study to determine the hemodynamic status, determining the gas composition, and acid-base balance of blood electrolytes before and after intensive therapy (group 1), using PD (group 2). Results: In group 1, the level of azotemia (creatinine clearance and urea clearance) persisted for more than 7 days, while in group 2, normalization of urea and creatinine clearance was observed even on the 4th day. Improvement of hemodynamic parameters (heart preload reduction by 22%) was observed in group 2. Improved gas exchange in lung function observed in the 2nd group.